蒋炳英

个人简介

蒋炳英,教授,硕士生导师。分别于1999年7月和2004年7月毕业于四川大学化学学院,获理学学士和博士学位。2004/10-2006/09于美国密歇根州立大学(MichiganState University)Dr. Denis Proshlyakov实验室进行博士后研究,研究内容为细胞色素C氧化酶中自由基电化学检测;2007/10-2008/4在美国亚利桑那州立大学(ArizonaState University)Dr. Qiang Chen课题组从事病毒免疫分析研究。2008年7月被引进到重庆理工大学化学化工学院工作,近年来主要从事生物传感和仿酶催化研究。目前主持国家自然科学基金和省部级自然科学基金各1项,主持完成2项省部级项目,参研国家级、省部级课题3项;近年来在Analytical Chemistry, Chemical Communications, Biosensors & Bioelectronics,Analyst, International Journal of Chemical Kinetics等国际知名期刊上发表论文20余篇。

研究领域

仿酶催化;电化学生物传感

承担的主要项目

[1]有害重金属离子高灵敏、多组分仿生电化学生物传感研究,国家自然科学基金青年科学基金项目(21505010),2016.1-2018.12,48万,主持。

[2]基于生物条形码纳米探针的高灵敏度多组分重金属离子电化学检测方法研究,重庆市科委自然科学基金一般项目(cstc2015jcyjA20026),2015.7-2018.6,7.5万,主持。

[3]镧系大环功能配合物模拟核酸酶催化动力学研究,重庆市科委自然科学基金一般项目(cstc2009BB5052),2009.7-2012.6,3万,主持。

[4]金属模拟酶催化磷酸酯水解的动力学研究,教育部第37批留学回国人员资助项目,2010.1-2012.12,3万,主持。

[5]具有官能团侧臂的氮杂冠醚金属配合物作为人工核酸酶催化DNA水解的构效关系,国家自然科学基金面上项目(21173274),2012.1-2015.12,63万,参与。

[6]新型芳香羧酸金属-有机配位聚合物晶体的水热合成与荧光性能研究,重庆市教委一般科技项目(KJ1400919),2014.1-2016.7,参与。

[7]重庆市教委一般科技项目“作为基因载体的新型可降解树枝状分子的合成及其构效研究”(KJ130820),参与。

[8]重庆理工大学科研创新团队“能源化工中新型催化材料的研制与应用”(2015TD22),2015.1-2017.12,20万,参与。

代表论文(*通讯作者)

[1] Min Wang, Fangzhen Li,Bingying Jiang*,Junqiang Xu, Shuo Li*, Yun Xiang, Ruo Yuan, Unmodified and positively chargedgold nanoparticles for sensitive colorimetric detection of folate receptor viaterminal protection of small molecule-linked ssDNA,Sci China Chem,2016, 59: 770–775.

[2]Bingying Jiang*, Fangzhen Li, CuiyunYang, Jiaqing Xie, Yun Xiang*, Ruo Yuan*, Aptamer Pseudoknot-FunctionalizedElectronic Sensor for Reagentless and Single-Step Detection of Immunoglobulin Ein Human Serum,Analytical Chemistry2015,87, 3094−3098.

[3]Bingying Jiang*, Min Wang, Fangzhen Li,Lan Yu, Jiaqing Xie, Multiplexed electrochemical coding of DNA–proteinbindings,Biosensors and Bioelectronics,2015, 64,429–433.

[4]Bingying Jiang*, Lan Yu, Fangzhen Li,Jiaqing Xie, A dual functional electrochemical “on–off” switch sensor for the detectionof mercury(II) and melamine,Sensors and Actuators B,2015, 212, 446–450.

[5]Bingying Jiang*, Min Wang, Li Ci, Jiaqing Xie*, Label-free and amplifiedaptasensor for thrombin detection based on background reduction and directelectron transfer of hemin,Biosensors & Bioelectronics,2013,43, 289-293.

[6]Bingying Jiang, Min Wang, Ying Chen, Jiaqing Xie*, Yun Xiang*, Highlysensitive electrochemical detection of cocaine on graphene/AuNP modifiedelectrode via catalytic redox-recycling amplification,Biosensors &Bioelectronics,2012, 32, 305-308.

[7]Mengli Yang,Bingying Jiang*, Jiaqing Xie, Yun Xiang*, Ruo Yuan, YaqinChai, Electrochemiluminescence recovery-based aptasensor for sensitiveOchratoxin A detection via exonuclease-catalyzed target recyclingamplification,Talanta,2014, 125, 45-50.

[8]Jin Xu,Bingying Jiang*, Jiaqing Xie, Yun Xiang*, Ruo Yuan, Yaqin Chai,Sensitive point-of-care monitoring of HIV related DNA sequences with a personalglucometer,Chemical Communications,2012, 48,10733-10735.

[9]Qiong Wang1,Bingying Jiang1, Jin Xu, Jiaqing Xie,Yun Xiang*, Ruo Yuan, Yaqin Chai, Amplified terminal protection assay of smallmolecule/protein interactions via a highly characteristic solid-state Ag/AgClprocess,Biosensors & Bioelectronics,2013, 43, 19-24.(Co-first author).

[10]Wang, Qiong,Jiang, Bingying*,Xie, Jiaqing,Xiang, Yun*,Yuan, Ruo,Chai, Yaqin,Coupling ofbackground reduction with rolling circle amplification for highly sensitiveprotein detection via terminal protection of small molecule-linked DNA,Analyst,2013, 138(19), 5751-5756.

[11]Bingying Jiang, Min Wang, Ci Li, Jiaqing Xie*, DNA-binding andhydrolytic cleavage promoted by tetraazamacycle La(III) and Ce(III) complexes,MedicinalChemistry Research,2013, 22, 3398–3404.

[12]Jiaqing Xie, Ci Li, Min Wang,Bingying Jiang*, Preparation of a newmetallomicelle catalyst for the hydrolysis of bis(4-nitrophenyl) phosphate,ChemicalPapers,2013, 67(4), 365-371.

[13]Jiaqing Xie, Ci Li, Min Wang,Bingying Jiang*, Construction and Activityof a New Catalytic System in the Hydrolysis of Bis(4-nitrophenyl) PhosphateEster,International Journal of Chemical Kinetics,2013,45(6), 397-403.

[14]Bingying Jiang, Shulan Cai, Famei Feng, Jiaqing Xie*, Spectral analysisand catalytic activity in the hydrolysis of the phosphate ester by aza-crownether cerium (III) complex,Journal of Chemical and PharmaceuticalResearch,2014, 6(3),1520-1526.

[15]Shuo Li, Jiaqing Xie,Bingying Jiang*, Liqun Zhang, Lan Yu, Fangzhen Liand Qingxiang Xiang*, Novel Zn(II) and Cu(II) complexes of the tetraaza-cyclododecanederivatives: Synthesis, characterization and catalytic activity,Journalof Chemical and Pharmaceutical Research,2014, 6(2), 742-752.

[16]Bingying Jiang, Famei Feng, Ci Li, Min Wang, Jiaqing Xie*,Characterization and Preparation of Well-dispersed TiO2 Nanoparticles byUltrasonic Microemulsion Method,Advanced Materials Research,2012,476-478, 1806-1810.

[17]Bingying Jiang, Famei Feng, Ci Li, Min Wang, Jiaqing Xie*, Comparativestudy of p-nitrophenyl picolinate hydrolysis catalyzed by Bis(O,O’-di(2- phenylalkyl)dithiophosphate) nickel(II),Advanced MaterialsResearch,2012,560-561, 305-308.