个人简介

张艺，博士，硕士生导师，讲师。本科和硕士就读于重庆大学，是重庆大学和加州大学旧金山分校联合培养博士。

研究方向

1. 肝癌机理研究及靶向药物研发

2. 筛选肝癌治疗药物及药效评价

代表性研究论文

[1]Zhang Y,Xu H, Cui G, Liang B, Chen X, Ko S, Affo S, Song X, Liao Y, Feng J, Wang P, Wang H, Xu M, Wang J, Pes GM, Ribback S, Zeng Y, Singhi A, Schwabe RF, Monga SP, Evert M, Tang L, Calvisi DF, Chen X. β-Catenin Sustains and Is Required for YES-associated Protein Oncogenic Activity in Cholangiocarcinoma.Gastroenterology.2022 Aug;163(2):481-494. (IF=33.883)

[2] Zhang L*,Zhang Y*,Shen D, Chen Y, Feng J, Wang X, Ma L, Liao Y, Tang L (*Co-first authors). RNA Binding Motif Protein 3 Promotes Cell Metastasis and Epithelial-Mesenchymal Transition Through STAT3 Signaling Pathway in Hepatocellular Carcinoma.Journal of Hepatocellular Carcinoma.2022 May 9; 9: 405-422. (IF=4.962)

[3] Xu X*,Zhang Y*, Wang X, Li S, Tang L (*Co-first authors). Substrate Stiffness Drives Epithelial to Mesenchymal Transition and Proliferation through the NEAT1-Wnt/β-Catenin Pathway in Liver Cancer.International Journal of Molecular Sciences.2021 Nov 8; 22(21): 12066. (IF=6.208)

[4]Zhang Y,Liang B, Song X, Wang H, Evert M, Zhou Y, Calvisi DF, Tang L, Chen X. Loss of Apc Cooperates with Activated Oncogenes to Induce Liver Tumor Formation in Mice.American Journal of Pathology.2021 May; 191(5): 930-946. (IF=5.770)

[5]Zhang Y,Solinas A, Cairo S, Evert M, Chen X, Calvisi DF. Molecular Mechanisms of Hepatoblastoma.Seminars in Liver Disease.2021 Jan; 41(1): 28-41.(IF=6.512)

[6] Wang H, Zhou Y, Xu H, Wang X,Zhang Y, Shang R, O'Farrell M, Roessler S, Sticht C, Stahl A, Evert M, Calvisi DF, Zeng Y, Chen X. Therapeutic efficacy of FASN inhibition in preclinical models of HCC.Hepatology.2022 Oct;76(4):951-966. (IF=17.425)

[7] Xu C, Xu Z,Zhang Y,Evert M, Calvisi DF and Chen X. β-Catenin signaling in hepatocellular carcinoma.The Journal of Clinical Investigation.2022 Feb 15; 132(4): e154515. (IF=19.456)

[8] Wang H, Zhang S,Zhang Y, Jia J, Wang J, Liu X, Zhang J, Song X, Che L, Ribback S, Cigliano A, Evert M, Liang B, Wu H, Calvisi DF, Zeng Y and Chen X. TAZ is indispensable for hepatocarcinogenesis induced by c-MYC.Journal of Hepatology. 2022 Jan; 76(1): 123-134. (IF=30.083)

联系方式

E-mail: zhangyi@cqut.edu.cn