药学与生物工程学院

李思奇

发布日期:2022-10-05 浏览量:

导 师 个 人 简 介

 

李思奇,博士、副教授、硕士生导师

学习与工作经历:

2010.09-2014.06,武汉工程大学,化工与制药学院,化学工程与工艺

2014.09-2020.06,西南大学,化学化工学院,分析化学(硕博连读)

2020.06-至今 重庆理工大学药学与生物工程学院

2023.02-至今 四川大学化学学院/重庆精准医疗产业技术研究院(博士后) 

教育教学情况

主讲《药物分析》、《药物分析实验》、《药事管理学》等本科课程,其中,《药物分析》课程入选重庆理工大学一流课程。参与或主持多个校级和市级教研教改、质量工程项目。曾获得重庆市2022年高校课程思政教学名师和团队、重庆理工大学第五届微课教学比赛三等奖、重庆理工大学“士继英才“、重庆理工大学优秀共产党员等荣誉称号。

学术成绩:

主要研究领域为:功能核酸;DNA纳米技术;仿生催化;精准医疗诊断

现任中国化学学会、中国生物物理学会会员。主持国家自然科学基金、中国博士后科学基金、重庆市教委、巴南区科技局等项目若干。以第一作者或通讯身份在ACS Appl. Mater. Inter.Biosens. Bioelectron.J. Hazard. Mater.国际高水平期刊发表论文7篇,3篇曾当选为ESI高被引论文。另,在Water Res.Chem. Eng. J.Chem. Coummun.Sensor. Actuat. B-Chem.等期刊参与发表SCI论文16,他引次数累计2000余次。 

代表性科研项目:

  1. 国家自然科学基金青年项目22206018,滚环扩增介导的比率荧光高灵敏传感平台构建及其对环境中痕量抗生素抗性基因检测研究,2023.01-2025.1230万,主持

  2. 中国博士后科学基金面上资助2023M740428,拆卸化学标记级联二维纳米酶构建ARGs的便携式灵敏检测平台研究2024.01.01-2025.12.308万,主持

  3. 重庆理工大学科研启动经费,2020ZDZ019,过渡态金属氧化物MOx(M=Fe,Co,Mn,Cu)晶面调控与其类酶催化活性之间构效关系研究,2021.01-2023.1240万,主持

  4. 重庆市教委科学技术研究项目(青年)KJQN2021011367,基于适体及DNA分子机器的比率荧光探针用于乳腺癌的诊断和分子分型,2021.10-2024.094万,参与

  5. 巴南区科技局科技项目,抗耐药鲍曼不动杆菌感染的抗菌肽喷雾剂开发,2021.10-2023.0910万,参与

  6. 重庆市技术创新与应用示范一般项目,cstc2018jscx-msybX0374,乡镇分散式污水处理技术研究与示范,2018-202120万,参与

  7. 重庆市技术创新与应用示范专项重点研发项,cstc2018jszx-zdyfxmX0010,重庆海绵城市建设与运维技术研究与示范,2018-2021150万,参与

代表性研究论文:

  1. S. Li, Y. Wei, Y. Wang, H. Liang. Advances in hydrophilic metal–organic frameworks for N-linked glycopeptide enrichment, Front. Chem. 2023, 59, 2126-2129.

  2. X. Tao, X. Chen, S. Cai, F. Yan, S. Li*, S. Jin*, H. Zhu, A multifunctional heterogeneous superwettable coating for water collection, oil/water separation and oil absorption. J. Hazard. Mater. 2023, 443, 130166.

  3. H. Zhu, S. Cai, J. Zhou, S. Li, D. Wang, J. Zhu, Y. Wu, Y. Huang, S. Yuan, S. Jin, F. Xia, Integration of water collection and purification on cactus- and beetle-inspired eco-friendly superwettable materials. Water Res. 2021, 206, 117759.

  4. X.Yang, X. Xie, S. Li, W. Zhang, X. Zhang, H. Chai, Y. Huang, The POM@ MOF hybrid derived hierarchical hollow Mo/Co bimetal oxides nanocages for efficiently activating peroxymonosulfate to degrade levofloxacin. J. Hazard. Mater. 2021, 419, 126360.

  5. S. Li, Y. Hou, Q. Chen, X. Zhang, H.Cao, Y. Huang, Promoting active sites in MOFs-derived homobimetallic hollow nanocages as multifunctional catalyst for sensitive biosensing and efficient organic pollutants degradation, ACS Appl. Mater. Inter. 2020, 12(2), 2581-2590.

  6. Q. Chen, S. Li, Y. Liu, X. Zhang, Y. Tang, H. Chai, Y. Huang. Size-controllable Fe-N/C single-atom nanozyme with exceptional oxidase-like activity for sensitive detection of alkaline phosphatase. Sensor Actuat B-Chem. 2020, 305, 127511. ESI高被引

  7. L. Wang, S. Li, X. Zhang, Y. Huang, CoSe2 hollow microspheres with superior oxidase-like activity for ultrasensitive colorimetric biosensing, Talanta 2020, 216, 121009.

  8. W. Li, S. Li, Y. Tang, X. Yang, W. Zhang, X. Zhang, H. Chai, Y. Huang, Highly efficient activation of peroxymonosulfate by cobalt sulfide hollow nanospheres for fast ciprofloxacin degradation. J. Hazard. Mater. 2020, 389, 121856.

  9. Q. Chen, X. Zhang, S. Li, J. Tan, C. Xu, Y. Huang, MOF-derived Co3O4@Co-Fe oxide double-shelled nanocages as multi- functional specific peroxidase-like nanozyme catalysts for chemo/biosensing and dye degradation. Chem. Eng. J. 2020, 395, 125130. ESI高被引

  10. S. Li, X. Hu, Q. Chen, X. Zhang, H. Chai, Y. Huang, Introducing bifunctional metal-organic frameworks to the construction of a novel ratiometric fluorescence sensor for screening acid phosphatase activity, Biosens. Bioelectron. 2019, 137, 133-139.

  11. S. Li, H. Chai, Y. Huang, Recent advances in the construction and analytical applications of metal-organic frameworks-based nanozymes, TRAC-Trend Anal. Chem. 2018, 105, 391-403. ESI高被引

  12. X. Zhang, X. Mao, S. Li, W. Dong, Y. Huang, Tuning the oxidase mimics activity of manganese oxides via control of their growth conditions for highly sensitive detection of glutathione, Sensor. Actuat. B-Chem. 2018, 258, 80-87.

  13. S. Li, L. Wang, X. Zhang, H. Chai, Y. Huang, A Co,N co-doped hierarchically porous carbon hybrid as a highly efficient oxidase mimetic for glutathione detection, Sensor. Actuat. B-Chem. 2018, 264,312-319. ESI高被引

  14. W. Dong, Y. Zhuang, S. Li, X. Zhang, H. Chai, Y. Huang, High peroxidase-like activity of metallic cobalt nanoparticles encapsulated in metal-organic frameworks derived carbon for biosensing, Sensor. Actuat. B-Chem. 2018, 255, 2050-2057.

  15. S. Li, X. Zhang, Y. Huang, Zeolitic imidazolate framework-8 derived nanoporous carbon as an effective and recyclable adsorbent for removal of ciprofloxacin antibiotics from water, J. Hazard. Mater. 2017, 321, 711-719. ESI高被引

    联系方式:

    E-mail: lisiqi47@cqut.edu.cn